Manufactured via enzymatic hydrolysis with tight MW control. Batch-specific test reports available on request.
| Parameter | Specification |
|---|---|
| Molecular Weight | < 10,000 Da (Small MW grade) |
| Appearance | White to off-white powder |
| Assay (GlcA method) | ≥ 90% |
| Loss on Drying | ≤ 10% |
| Heavy Metals | ≤ 20 ppm |
| Arsenic | ≤ 2 ppm |
| Microbial Count | ≤ 100 CFU/g |
| pH (1% solution) | 5.5 – 7.5 |
| Solubility | Freely soluble in water |
| Protein Content | ≤ 0.1% |
Fragments in the 50–100 kDa range activate CD44 receptor signaling and modulate inflammatory cytokine cascades — well-documented in dermatology research.
Upregulates genes involved in tissue repair and promotes keratinocyte migration for accelerated wound closure.
Smaller than standard HA, this grade permeates the epidermis for targeted delivery without requiring enhancers or chemical modification.
Low-MW HA fragments promote new blood vessel formation — important for tissue regeneration and wound repair.
Extensively studied for cosmeceutical and pharmaceutical applications — strong scientific dossier available for regulatory submissions.
Dermatologist-recommended formulations where anti-inflammatory and skin-repairing claims require scientific backing.
Soothing preparations after laser resurfacing, chemical peels, or microneedling treatments.
Formulations targeting rosacea, eczema-prone, or reactive skin where reducing inflammation is the primary goal.
Medical-grade topicals and wound dressings leveraging HA fragment bioactivity for tissue repair.
Targets inflammation associated with acne without disrupting the skin microbiome.
Bioavailable form for joint and skin health supplements where anti-inflammatory efficacy is a key claim.
< 800 Da — deepest penetration for high-performance anti-aging and cosmeceuticals.
Learn More →< 3,000 Da — enzymatic hydrolysis grade with unique bioactive fragment activity.
Learn More →10,000 – 400,000 Da — versatile grade for daily moisturizers and oral supplements.
Learn More →1,500,000 – 2,200,000 Da — protective film-forming for intensive surface moisturization.
Learn More →Contact our team for samples, batch COA, full scientific dossier, and pricing based on your required specification and volume.