Cosmetic Grade Fermentation-Derived Low Microbial High Clarity COA Available

Cosmetic Grade Sodium Hyaluronate

Ultra-pure fermentation-derived sodium hyaluronate optimized for topical skincare and personal care formulations — featuring exceptional water solubility, high clarity in aqueous solutions, and strict low-endotoxin and low-microbial specifications.

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≥ 90%
Assay
Cosmetic
Grade
Fermentation
Source
9067-32-7
CAS No.
📄 Product Documents: ⬇ Certificate of Analysis (COA) ⬇ Product Datasheet TDS / MSDS / Certificates: ✉ Contact Us to Request

Certificate of Analysis

Cosmetic grade specification with stricter microbial and clarity controls versus food grade. Actual COA provided per batch upon request.

Test Item Result / Specification
Identification & Appearance
Appearance White or almost white powder or granule
Transmittance T₅₅₀ₙₘ ≥ 99.0%
Absorbance A₂₈₀ₙₘ ≤ 0.25
Chemical Assay
Sodium Hyaluronate Content ≥ 92.0%
Glucuronic Acid Content ≥ 44.5%
Intrinsic Viscosity Measured value (reported)
Average Molecular Weight Per grade specification
Physical & Chemical Properties
pH (5 mg/mL, 25°C) 5.0 – 8.5
Loss on Drying ≤ 10.0%
Protein Content ≤ 0.1%
Heavy Metals
Mercury (as Hg) ≤ 1.0 mg/kg
Lead (as Pb) ≤ 10.0 mg/kg
Arsenic (as As) ≤ 2.0 mg/kg
Cadmium (as Cd) ≤ 5.0 mg/kg
Microbiological
Total Aerobic Count ≤ 100 CFU/g
Molds & Yeasts ≤ 50 CFU/g
Staphylococcus aureus Negative / g
Pseudomonas aeruginosa Negative / g
Thermotolerant Coliform Bacteria Negative / g
Packaging & Storage
Packaging 1 kg / 5 kg / 25 kg
Storage Condition Cool, dry, away from light
Shelf Life 36 months

📌 Available Molecular Weight Grades

MW Grade Range Skin Function Recommended Application
Nano HA < 800 Da Deep dermal penetration Anti-aging serums, transdermal actives
Hydrolyzed HA < 3,000 Da Enhanced absorption, low viscosity Lightweight essences, toners, ampoules
Low MW HA 10,000 – 400,000 Da Barrier repair, moisturizing Creams, lotions, emulsions
Medium MW HA 400,000 – 1,500,000 Da Film-forming, long-lasting hydration Rich moisturizers, gel textures
High MW HA 1,500,000 – 2,200,000 Da Surface film, water-locking Hydrogel masks, thick gel formulas

ⓘ Multi-weight HA blends (e.g. Nano + High MW) available for multi-layer hydration formulations. Inquire for custom blending options.

Product Advantages

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Fermentation-Derived Purity

Produced via microbial fermentation — no animal tissue, no risk of animal-derived contaminants. Delivers a structurally consistent HA with traceable, documented production process.

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Superior Aqueous Clarity

Exceptional solubility and transparency in aqueous systems — forms clear, particle-free solutions ideal for serums, essences, and gel formulations where visual clarity is critical.

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Strict Microbial Control

Meets ISO cosmetic microbiological standards: Total Aerobic Count ≤ 100 CFU/g, Pseudomonas aeruginosa and Staphylococcus aureus absent — fully compliant with EU Cosmetics Regulation.

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EU Cosmetics Regulation Compliant

Heavy metal limits aligned with EU Cosmetics Regulation (EC) No 1223/2009 — particularly Pb ≤ 2 ppm and Hg ≤ 0.1 ppm. Full INCI documentation available.

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Multiple MW Grades in One Source

From Nano HA (< 800 Da) for deep penetration to High MW HA (> 1,500,000 Da) for surface film-forming — all grades from a single, audited manufacturing site.

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Low Protein Content

Protein content ≤ 0.1% minimizes sensitization risk in cosmetic formulations — an important parameter for products targeting sensitive skin and clean beauty positioning.

Formulation Applications

Cosmetic grade sodium hyaluronate is a versatile active ingredient used across all major skincare and personal care product categories.

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Serums & Essences

Lightweight aqueous formulas where high MW HA provides surface hydration and nano/low MW grades deliver deep penetration — the ideal multi-layer hydration system.

Anti-Aging Creams

Combined with retinol, peptides, or niacinamide in premium anti-aging formulations. HA provides the hydration matrix that improves the tolerability and delivery of active ingredients.

🎭

Sheet Masks & Hydrogels

High MW HA is the backbone of hydrogel and sheet mask formulations — its exceptional water-binding capacity (up to 1,000× its weight) delivers an intensive hydration effect.

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Color Cosmetics

Used in foundations, BB creams, and lip products to improve texture, spreadability, and skin-feel. Low MW grades preferred for their compatibility with pigment systems.

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Toners & Mists

Water-soluble, non-sticky hydration layer applied before serum and moisturizer steps. Hydrolyzed HA and nano HA grades are ideal for toners and facial mist applications.

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Eye & Lip Care

Fragrance-free, low-irritation formulations for sensitive periocular and lip areas — HA provides plumping hydration with minimal sensitization risk at these application sites.

☀️

Sunscreens

Incorporated into SPF emulsions to offset the potential drying effect of UV filters, improve skin feel, and contribute to the overall moisturization profile of the formula.

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Cleansers & Rinse-Off

Low MW HA added to facial cleansers, micellar waters, and rinse-off treatments to maintain the skin barrier moisture level post-cleansing.

Other Sodium Hyaluronate Grades

🇪🇺

European Union

INCI name: Sodium Hyaluronate. Fully compliant with EU Cosmetics Regulation (EC) No 1223/2009. Heavy metal limits and microbial specifications meet Annex I safety requirements.

🇺🇸

United States

Listed under FDA 21 CFR as a cosmetic ingredient. INCI-named, suitable for use in OTC cosmetic products. No pre-market approval required for cosmetic applications.

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Asia Pacific

Approved cosmetic ingredient in China (IECIC listed), Japan, South Korea (MFDS), and Australia (AICS). Full dossier support for NMPA China registration available.

Other Sodium Hyaluronate Grades

Food Grade HA

Fermentation-derived, GRAS — for dietary supplements, functional foods and oral beauty products.

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Pharmaceutical Grade HA

USP/EP compliant GMP grade — for oral pharmaceutical and medical device applications.

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Eye-Drop Grade HA

Endotoxin-controlled (< 0.5 IU/mg) — for artificial tears and eye-drop solutions.

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Injectable Grade HA

Ultra-high purity sterile grade — for dermal fillers and joint injections.

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Ready to Source Cosmetic Grade Sodium Hyaluronate?

Contact our team to receive samples, batch COA, INCI documentation, and pricing based on your required molecular weight grade and order volume.

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