Injectable Grade EP 11.0 Compliant Ultra-Low Endotoxin BSE/TSE Certified GMP Facility

Injectable Grade Chondroitin Sulfate

Ultra-pure injectable-grade Chondroitin Sulfate Sodium, specifically developed for parenteral applications and sterile medical devices. Strictly controlled for endotoxins, protein, and microbial bioburden to ensure clinical safety.

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95.0–105.0%
Assay
EP 11.0
Standard
< 0.05 EU/mg
Endotoxin
Bovine
Source
📄 Product Documents: ⬇ Certificate of Analysis (COA) ⬇ Product Datasheet TDS / MSDS / Certificates: ✉ Contact Us to Request

Certificate of Analysis

Compliant with EP 11.0 standards for parenteral applications. Actual batch COA provided upon inquiry.

Test Item Result / Specification
Identification & Appearance
Appearance White to off-white free flowing powder
Particle Size 100% pass 80 mesh
Identification A (IR) Conforms to reference standard
Identification B (Na) Positive sodium salt reaction
Identification C (Electrophoretogram) Conforms
Clarity (5% solution) Absorbance ≤ 0.35
Chemical Assay
Assay (CPC, dried basis) 95.0% – 105.0%
Electrophoretic Purity Individual impurity ≤ 2%
Specific Rotation -20.0° to -30.0°
Physical & Chemical
pH (1% solution) 5.5 – 7.5
Loss on Drying ≤ 12.0%
Protein (dried basis) ≤ 3.0%
Chloride ≤ 0.50%
Sulfate ≤ 0.24%
Residue on Ignition 20.0% – 30.0%
Microbiological & Endotoxin
Total Plate Count ≤ 100 CFU/g
Yeasts & Molds ≤ 50 CFU/g
E. coli Negative
Salmonella Negative
Pseudomonas aeruginosa Negative
Bacterial Endotoxins < 0.05 EU/mg
Packaging & Storage
Packaging 1 kg / 5 kg
Storage Cool, dry, away from light
Shelf Life 24 months

Product Advantages

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Highest Grade CS Available

Injectable grade represents the strictest purity specification for chondroitin sulfate — meeting EP 11.0 standard for parenteral application starting materials.

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Endotoxin < 0.05 EU/mg

The strictest endotoxin limit across all CS grades — tested by LAL method per EP 2.6.14, ensuring safety for intra-articular and parenteral applications.

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Ultra-Low Protein (≤ 3.0%)

Minimizes immunogenic risk in injectable formulations — critical for patient safety in intra-articular injection drug products.

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Near-Sterile Profile

Total Plate Count ≤ 100 CFU/g, Molds ≤ 50 CFU/g — providing minimal bioburden for subsequent aseptic processing steps.

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Full BSE/TSE Documentation

Bovine source with complete TSE risk assessment, raw material traceability, and supplier audit documentation for Class III medical device submissions.

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Complete Regulatory Package

COA per batch, endotoxin test report, electrophoretogram, GMP certificate, BSE/TSE declaration, and MSDS available for regulatory filings.

Injectable Applications

Pharmacopoeia grade Chondroitin Sulfate for parenteral drug products and sterile Class III medical devices.

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Intra-Articular Injection

The primary injectable CS application — viscosupplementation drug products for osteoarthritis treatment injected directly into the joints.

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Sterile Medical Devices

Class III injectable medical devices requiring EP-grade starting materials with documented endotoxin control and full supply chain traceability.

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Combination Injectable Formulas

Co-formulated with injectable-grade hyaluronic acid in combination viscosupplementation products for enhanced joint lubrication.

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Pharmaceutical R&D

Starting material for parenteral formulation development, stability studies, and clinical trial manufacturing of injectable joint therapy products.

Other Chondroitin Sulfate Grades

Pharmaceutical Grade CS

EP compliant grade for oral drug products and medical device applications.

Learn More →

Food Grade CS

USP 43 compliant grade for standard dietary joint health supplements.

Learn More →

Injectable Grade HA

Ultra-pure sterile Sodium Hyaluronate for joint injections and dermal fillers.

Learn More →

Bovine Chondroitin Sulfate

High-quality bovine source material with documented purity and origin.

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Ready to Source Injectable Grade Chondroitin Sulfate?

Contact our parenteral product specialists to receive technical dossiers, endotoxin reports, and samples for your injectable product development.

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